Chronic otitis media: a new extra-articular manifestation in ankylosing spondylitis?
نویسندگان
چکیده
Following a study reporting a fourfold increase in the occurrence of chronic otitis media in patients with ankylosing spondylitis, this prospective study examines this association with respect to severity, duration of disease, and acute phase in ankylosing spondylitis. Forty two consecutive patients with classical ankylosing spondylitis seen at the rheumatology clinic of a teaching hospital where the features of ankylosing spondylitis were recorded had an otological examination by an otolaryngologist. The occurrence of chronic otitis media (all categories) was 12/42 (29%). The acute phase serum markers (C reactive protein and IgG) were increased in patients with active or inactive chronic otitis media. Extra-articular manifestations were significantly more common in the chronic otitis media group than in those with no history of chronic otitis media. The results of this study suggest that chronic otitis media may be another extra-articular manifestation of ankylosing spondylitis. Alternative explanations, however, include similar aetiological factors for the two conditions or a previously unrecognised increased occurrence of HLA-B27 in patients with chronic otitis media.
منابع مشابه
Frequency of cardiac involvement among patients with Ankylosing Spondylitis
Background and aims: Ankylosing spondylitis (AS) is an idiopathic chronic inflammatory disease mainly involves sacroiliac and axial joints; but it may also have extra-articular involvement. Accordingly, this study was designed to determine the frequency of cardiac involvement among patients with ankylosing spondylitis. Methods: This study was performed as a descriptive-analytical cross-se...
متن کاملProgressive Pulmonary Fibrocystic Changes of Both Upper Lungs in a Patient with Ankylosing Spondylitis
Ankylosing spondylitis is a chronic inflammatory multisystem disease that primarily affects the axial joints. Pleuropulmonary involvement is an uncommon extra-articular manifestation of ankylosing spondylitis. There is a wide spectrum of pulmonary parenchymal changes in ankylosing spondylitis, beginning in the early stages of the disease and increasing over time. The lesions are usually asympto...
متن کاملAnkylosing spondylitis and uveitis: overview.
The present article reviews the epidemiology, pathogenesis, clinical features, diagnosis, and treatment of ankylosing spondylitis and its association with ocular changes. The authors used the PubMed (MEDLINE), LILACS, and Ophthalmology Library databases. Ankylosing spondylitis is a chronic inflammatory disease that usually affects the axial skeleton and can progress to stiffness and progressive...
متن کاملAnkylosing spondylitis and other spondyloarthropathies: extra-articular manifestations and their management
It is especially relevant that we acknowledge that in the same patient we can find any of the four syndromes, or all of them in diverse combinations. Ankylosing spondylitis is a chronic systemic inflammatory disorder, with an estimated preva lence of 0.2–1.2%, involving the sacroiliac (SI) joints, the spine, and often the hips or peripheral joints, which predominantly affects young men. In the...
متن کاملCardiopulmonary Manifestations of Ankylosing Spondylitis
Ankylosing spondylitis is a chronic inflammatory condition that usually affects young men. Cardiac dysfunction and pulmonary disease are well-known and commonly reported extra-articular manifestation, associated with ankylosing spondylitis (AS). AS has also been reported to be specifically associated with aortitis, aortic valve diseases, conduction disturbances, cardiomyopathy and ischemic hear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 51 5 شماره
صفحات -
تاریخ انتشار 1992